ПРИМЕНЕНИЕ ИНДОЦИАНИНА ЗЕЛЕНОГО В ДИАГНОСТИКЕ И ЛЕЧЕНИИ РАКА ЖЕЛУДКА
Обзорная статья
Дата публикации: февраля 9, 2023
Ключевые слова
рак желудка
индоцианин зеленый
флуоресцентная лимфография
индоцианин зеленый
флуоресцентная лимфография
Как цитировать
[1]
Р. Е. Израилов, И. Р. Мухаев, Н. Е. Семенов, Д. А. Матвейчук, и А. В. Андрианов, ПРИМЕНЕНИЕ ИНДОЦИАНИНА ЗЕЛЕНОГО В ДИАГНОСТИКЕ И ЛЕЧЕНИИ РАКА ЖЕЛУДКА, КМКВ, вып. 4, сс. 49-52, фев. 2023.
Аннотация
Индоцианин зеленый - это цианиновый краситель, используемый при флуоресцентной хромоскопии. Данное контрастное вещество используется во многих направлениях хирургии, в том числе при диагностике и лечении рака желудка. По данным мировой литературы, для окрашивания интересующих структур могут применяться несколько методик введения индоцианина зеленого: системно – внутривенно и локально – в подслизистую и подсерозную оболочки желудка. Применение ICG/NIR-флуоресцентная визуализация является достаточно перспективной методикой, которая сочетает в себе низкую токсичность, безопасность и простоту использования, низкую стоимость. Она может помочь в обнаружении лимфоузлов и определении линии резекции, снизить частоту операционных осложнений за счет адекватной оценки кровоснабжения ремнанта в ходе реконструктивного этапа, сократить время оперативного вмешательства благодаря улучшению качества визуализации анатомических структур. Однако, накопленный опыт использования индоцианина зеленого (ложноотрицательные результаты в силу различных причин, отсутствие сравнительной оценки в различных популяциях пациентов) свидетельствует о необходимости дальнейших исследований в области применения данного контрастного вещества.Литература
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2. Reinhart M. B. et al. Indocyanine green: historical context, current applications, and future considerations //Surgical innovation. – 2016. – V. 23. – №. 2. – P. 166-175. doi: 10.1177/1553350615604
3. Kanuri A., Liu A. S., Guo L. Whom should we SPY? A cost analysis of laser-assisted indocyanine green angiography in prevention of mastectomy skin flap necrosis during prosthesis-based breast reconstruction //Plastic and reconstructive surgery. – 2014. – V. 133. – №. 4. – P. 448e-454e. doi: 10.1097/PRS0000000000000025
4. Kaburagi T. et al. Intraoperative fluorescence lymphography using indocyanine green in a patient with chylothorax after esophagectomy: report of a case //Surgery today. – 2013. –V. 43. – №. 2. – P. 206-210. doi: 10.1007/s00595-012-0391-6
5. Kamiya K., Unno N., Konno H. Intraoperative indocyanine green fluorescence lymphography, a novel imaging technique to detect a chyle fistula after an esophagectomy: report of a case //Surgery Today. – 2009. – V. 39. – №. 5. – P. 421-424. doi: 10.1007/s00595-008-3852-1
6. Yannuzzi L. A. Indocyanine green angiography: a perspective on use in the clinical setting //American journal of ophthalmology. – 2011. – V. 151. – №. 5. – P. 745-751. e1. doi: 10.1016/j.ajo.2011.01.043
7. Desiderio J. et al. Fluorescence image-guided lymphadenectomy using indocyanine green and near infrared technology in robotic gastrectomy //Chinese Journal of Cancer Research. – 2018. – V. 30. – №. 5. – P. 568. doi: 10.21147/j.issn.1000-9604.2018.05.11
8. Chen Q. Y. et al. Safety and efficacy of indocyanine green tracer-guided lymph node dissection during laparoscopic radical gastrectomy in patients with gastric cancer: a randomized clinical trial //JAMA surgery. – 2020. – V. 155. – №. 4. – P. 300-311. doi: 10.1001/jamasurg.2019.6033
9. Baiocchi G. L. et al. Fluorescence-guided lymphadenectomy in gastric cancer: a prospective western series //Updates in surgery. – 2020. – V. 72. – №. 3. – P. 761-772. doi: 10.1007/s13304-020-00836-0
10. Romanzi A. et al. ICG‐NIR‐guided lymph node dissection during robotic subtotal gastrectomy for gastric cancer. A single‐centre experience //The International Journal of Medical Robotics and Computer Assisted Surgery. – 2021. – V. 17. – №. 2. – P. e2213. doi: 10.1002/rcs.2213
11. Cianchi F. et al. The clinical value of fluorescent lymphography with indocyanine green during robotic surgery for gastric cancer: a matched cohort study //Journal of Gastrointestinal Surgery. – 2020. – V. 24. – №. 10. – P. 2197-2203. doi: 10.1007/s11605-019-04382-y
12. Kwon I. G. et al. Fluorescent lymphography–guided lymphadenectomy during robotic radical gastrectomy for gastric cancer //JAMA surgery. – 2019. – V. 154. – №. 2. – P. 150-158. doi: 10.1001/jamasurg.2018.4267
13. Park S. H. et al. Near-infrared fluorescence-guided surgery using indocyanine green facilitates secure infrapyloric lymph node dissection during laparoscopic distal gastrectomy //Surgery Today. – 2020. – V. 50. – №. 10. – P. 1187-1196. doi: 10.1007/s00595-020-01993-w
14. Huang Z. N. et al. Assessment of indocyanine green tracer-guided lymphadenectomy in laparoscopic gastrectomy after neoadjuvant chemotherapy for locally advanced gastric cancer: results from a multicenter analysis based on propensity matching //Gastric Cancer. – 2021. – V. 24. – №. 6. – P. 1355-1364. doi: 10.1007/s10120-021-01211-7
15. Tanaka C. et al. Detection of indocyanine green fluorescence to determine tumor location during laparoscopic gastrectomy for gastric cancer: Results of a prospective study //Asian journal of endoscopic surgery. – 2020. – V. 13. – №. 2. – P. 160-167. doi: 10.1111/ases.12710
16. Kim M. et al. Real-time vessel navigation using indocyanine green fluorescence during robotic or laparoscopic gastrectomy for gastric cancer //Journal of gastric cancer. – 2017. – V. 17. – №. 2. – P. 145-153. doi: 10.5230/jgc.2017.17.e17
17. Ushimaru Y. et al. The feasibility and safety of preoperative fluorescence marking with indocyanine green (ICG) in laparoscopic gastrectomy for gastric cancer //Journal of Gastrointestinal Surgery. – 2019. – V. 23. – №. 3. – P. 468-476. doi: 10.1007/s11605-018-3900-0
18. Park J. H. et al. Mapping of the perigastric lymphatic network using indocyanine green fluorescence imaging and tissue marking dye in clinically advanced gastric cancer //European Journal of Surgical Oncology. – 2022. – V. 48. – №. 2. – P. 411-417. doi: 10.1016/j.ejso.2021.08.029
19. Takahashi N. et al. Laparoscopic sentinel node navigation surgery for early gastric cancer: a prospective multicenter trial //Langenbeck's archives of surgery. – 2017. – V. 402. – №. 1. – P. 27-32. doi: 10.1007/s00423-016-1540-y
20. Карачун А. М., Пелипась Ю. В., Асадчая Д. П. Биопсия сигнальных лимфатических узлов при раннем раке желудка //Злокачественные опухоли. – 2020. – V. 10. – №. 3S1. – P. 21-24. [Karachun A. M., Pelipas Y.V., Asadchaya D. P. Biopsy of signal lymph nodes in early gastric cancer. Malignant tumors. 2020. V.10 3s1. P.21–24. In Russian.] doi: 10.37469/0507-3758-2018-64-3-335-344
21. Huang Y., Pan M., Chen B. A systematic review and meta-analysis of sentinel lymph node biopsy in gastric cancer, an optimization of imaging protocol for tracer mapping //World Journal of Surgery. – 2021. – V. 45. – №. 4. – P. 1126-1134. doi: 10.1007/s00268-020-05900-9
22. Kamada T. et al. A new method of sentinel node mapping for early gastric cancer using a fluorescent laparoscope that can adjust the intensity of excitation light and quantify the intensity of indocyanine green fluorescence: report of a case //International Journal of Surgery Case Reports. – 2020. – V. 73. – P. 248-252. doi: 10.1016/j.ijscr.2020.07.045
23. Sakamoto E. et al. Indocyanine green imaging to guide lymphadenectomy in laparoscopic distal gastrectomy-With vídeo //Annals of Medicine and Surgery. – 2021. – V. 69. – P. 102657. doi: 10.1016/j.amsu.2021.102657