Динамика вариабельности сердечного ритма у пациентов после ортотопической трансплантации сердца
Обследование кардиологических больных
Дата публикации: марта 14, 2018
Ключевые слова
трансплантированное сердце
денервация
реиннервация миокарда
вариабельность сердечного ритма
денервация
реиннервация миокарда
вариабельность сердечного ритма
Как цитировать
Лепшокова М. Х., Космачева Е. Д., Порханов В. А. Динамика вариабельности сердечного ритма у пациентов после ортотопической трансплантации сердца // Кремлевская медицина. Клинический вестник. 2018. Т. № 1. С. 84-88.
Аннотация
Реиннервация трансплантированного сердца является одним из малоизученных феноменов современной медицины. Проводимые в данной области исследования имеют противоречивые результаты относительно сроков ее возникновения и динамики. Наиболее доступной и специфичной методикой изучения процесса реиннервации является исследование вариабельности ритма сердца. В данной статье представлены результаты исследования феномена реиннервации сердечного аллографта посредством анализа показателей вариабельности сердечного ритма в динамике у пациентов после трансплантации сердца.Литература
1. Покровский В.М. и соавт. Оценка функциональной адаптации трансплантированного сердца в организме реципиента. Кубанский научный медицинский вестник. 2014; 6: 62-65.
2. «Трансплантация сердца» Национальные клинические рекомендации, М., 2013.
3. Bernardi L. et al. Influence of Type of Surgery on the Occurrence of Parasympathetic Reinnervation After Cardiac Transplantation. Circulation. 1998; 97 (14): 1368-1374.
4. Beckers F. et al. Different Evolutions in Heart Rate Variability after Heart Transplantation: 10-Year Follow-Up. Transplantation. 2004; 78 (10): 1523-1531.
5. Bengel F. et al. Serial Assessment of Sympathetic Reinnervation After Orthotopic Heart Transplantation : A Longitudinal Study Using PET and C-11 Hydroxyephedrine. Circulation. 1999; 99 (14): 1866-1871.
6. Bengel F. et al. Effect of Sympathetic Reinnervation on Cardiac Performance after Heart Transplantation. New Engl. J. Med. 2001; 345 (10): 731-738.
7. Braith R. et al. Abnormal neuroendocrine responses during exercise in heart transplant recipients. Circulation. 1992; 86 (5): 1453-1463.
8. Buendia-Fuentes F. et al. Sympathetic Reinnervation 1 Year After Heart Transplantation, Assessed Using Iodine-123 Metaiodobenzylguanidine Imaging. Transplantation Proceedings. 2011; 43 (6): 2247-2248.
9. Cornelissen V. et al. Heart rate variability after heart transplantation: A 10-year longitudinal follow-up study. J. Cardiol. 2012; 59 (2): 220-224.
10. Electrophysiology T. Heart Rate Variability: Standards of Measurement, Physiological Interpretation, and Clinical Use. Circulation. 1996; 93 (5): 1043-1065.
11. Halpert I. et al. Reinnervation of the transplanted human heart as evidenced from heart rate variability studies. Amer. J. Cardiol. 1996; 77 (2): 180-183.
12. Hayman M. et al. Understanding exercise-induced hyperemia: central and peripheral hemodynamic responses to passive limb movement in heart transplant recipients. AJP: Heart and Circulat. Physiol. 2010; 299 (5): H1653-H1659.
13. Hunt S. Current Status of Cardiac Transplantation. J.A.M.A. 1998; 280 (19): 1692.
14. Imamura T. et al. Parasympathetic Reinnervation Accompanied by Improved Post-Exercise Heart Rate Recovery and Quality of Life in Heart Transplant Recipients. Intern. Heart J. 2015; 56 (2): 180-185. 15. Imamura T. et al. Recipients With Shorter Cardiopulmonary Bypass Time Achieve Improvement of Parasympathetic Reinnervation Within 6 Months After Heart Transplantation. J. Heart Lung Transplant. 2015; 34 (4): S293.
16. Keeley E., Toth Z., Goldberg A. Long-term assessment of heart rate variability in cardiac transplant recipients. J. Heart Lung Transplant. 2000; 19 (3): 310-312.
17. Kоndo Y., Matheny J., Hardy J. Autonomic Reinnervation of Cardiac Transplants. Ann. Surgery. 1972; 176 (1): 42-48.
18. Lovric S. et al. Sympathetic reinnervation after heart transplantation, assessed by iodine-123 metaiodobenzylguanidine imaging, and heart rate variability. Eur. J. Cardio-Thoracic Surgery. 2004; 26 (4): 736-741.
19. Mohanty P. et al. Impairment of cardiopulmonary baroreflex after cardiac transplantation in humans. Circulation. 1987; 75 (5): 914-921.
20. Raczak G. Arterial baroreflex modulation of heart rate in patients early after heart transplantation: lack of parasympathetic reinnervation. J. Heart Lung Transplant. 1999; 18 (5): 399-406.
21. Roper S.Taylor B. Reinnervation of denervated parasympathetic neurons in cardiac ganglia from Rana pipiens. J. Physiol. 1982; 326 (1): 155-171.
22. Sands K. et al. Power spectrum analysis of heart rate variability in human cardiac transplant recipients. Circulation. 1989; 79 (1): 76-82.
23. Savin W. et al. Cardiorespiratory responses of cardiac transplant patients to graded, symptom-limited exercise. Circulation. 1980; 62 (1): 55-60.
24. Schwaiger M. et al. Evidence for regional catecholamine uptake and storage sites in the transplanted human heart by positron emission tomography. J. Clin. Invest. 1991; 87 (5): 1681-1690.
25. Stehlik J. et al. The Registry of the International Society for Heart and Lung Transplantation: 29th Official Adult Heart Transplant Report—2012. J. Heart and Lung Transplant. 2012; 31 (10): 1052-1064. 26. Toledo E. et al. Functional restitution of cardiac control in heart transplant patients. Amer. J. Physiol - Regulatory, Integrative and Comparative Physiology. 2001; 282 (3): R900-R908.
27. Überfuhr P. Signs of vagal reinnervation 4 years after heart transplantation in spectra of heart rate variability. Eur. J. Cardio-Thoracic Surgery. 1997; 12 (6): 907-912.
28. Wilson R. et al. Evidence for structural sympathetic reinnervation after orthotopic cardiac transplantation in humans. Circulation. 1991; 83 (4): 1210-1220.
2. «Трансплантация сердца» Национальные клинические рекомендации, М., 2013.
3. Bernardi L. et al. Influence of Type of Surgery on the Occurrence of Parasympathetic Reinnervation After Cardiac Transplantation. Circulation. 1998; 97 (14): 1368-1374.
4. Beckers F. et al. Different Evolutions in Heart Rate Variability after Heart Transplantation: 10-Year Follow-Up. Transplantation. 2004; 78 (10): 1523-1531.
5. Bengel F. et al. Serial Assessment of Sympathetic Reinnervation After Orthotopic Heart Transplantation : A Longitudinal Study Using PET and C-11 Hydroxyephedrine. Circulation. 1999; 99 (14): 1866-1871.
6. Bengel F. et al. Effect of Sympathetic Reinnervation on Cardiac Performance after Heart Transplantation. New Engl. J. Med. 2001; 345 (10): 731-738.
7. Braith R. et al. Abnormal neuroendocrine responses during exercise in heart transplant recipients. Circulation. 1992; 86 (5): 1453-1463.
8. Buendia-Fuentes F. et al. Sympathetic Reinnervation 1 Year After Heart Transplantation, Assessed Using Iodine-123 Metaiodobenzylguanidine Imaging. Transplantation Proceedings. 2011; 43 (6): 2247-2248.
9. Cornelissen V. et al. Heart rate variability after heart transplantation: A 10-year longitudinal follow-up study. J. Cardiol. 2012; 59 (2): 220-224.
10. Electrophysiology T. Heart Rate Variability: Standards of Measurement, Physiological Interpretation, and Clinical Use. Circulation. 1996; 93 (5): 1043-1065.
11. Halpert I. et al. Reinnervation of the transplanted human heart as evidenced from heart rate variability studies. Amer. J. Cardiol. 1996; 77 (2): 180-183.
12. Hayman M. et al. Understanding exercise-induced hyperemia: central and peripheral hemodynamic responses to passive limb movement in heart transplant recipients. AJP: Heart and Circulat. Physiol. 2010; 299 (5): H1653-H1659.
13. Hunt S. Current Status of Cardiac Transplantation. J.A.M.A. 1998; 280 (19): 1692.
14. Imamura T. et al. Parasympathetic Reinnervation Accompanied by Improved Post-Exercise Heart Rate Recovery and Quality of Life in Heart Transplant Recipients. Intern. Heart J. 2015; 56 (2): 180-185. 15. Imamura T. et al. Recipients With Shorter Cardiopulmonary Bypass Time Achieve Improvement of Parasympathetic Reinnervation Within 6 Months After Heart Transplantation. J. Heart Lung Transplant. 2015; 34 (4): S293.
16. Keeley E., Toth Z., Goldberg A. Long-term assessment of heart rate variability in cardiac transplant recipients. J. Heart Lung Transplant. 2000; 19 (3): 310-312.
17. Kоndo Y., Matheny J., Hardy J. Autonomic Reinnervation of Cardiac Transplants. Ann. Surgery. 1972; 176 (1): 42-48.
18. Lovric S. et al. Sympathetic reinnervation after heart transplantation, assessed by iodine-123 metaiodobenzylguanidine imaging, and heart rate variability. Eur. J. Cardio-Thoracic Surgery. 2004; 26 (4): 736-741.
19. Mohanty P. et al. Impairment of cardiopulmonary baroreflex after cardiac transplantation in humans. Circulation. 1987; 75 (5): 914-921.
20. Raczak G. Arterial baroreflex modulation of heart rate in patients early after heart transplantation: lack of parasympathetic reinnervation. J. Heart Lung Transplant. 1999; 18 (5): 399-406.
21. Roper S.Taylor B. Reinnervation of denervated parasympathetic neurons in cardiac ganglia from Rana pipiens. J. Physiol. 1982; 326 (1): 155-171.
22. Sands K. et al. Power spectrum analysis of heart rate variability in human cardiac transplant recipients. Circulation. 1989; 79 (1): 76-82.
23. Savin W. et al. Cardiorespiratory responses of cardiac transplant patients to graded, symptom-limited exercise. Circulation. 1980; 62 (1): 55-60.
24. Schwaiger M. et al. Evidence for regional catecholamine uptake and storage sites in the transplanted human heart by positron emission tomography. J. Clin. Invest. 1991; 87 (5): 1681-1690.
25. Stehlik J. et al. The Registry of the International Society for Heart and Lung Transplantation: 29th Official Adult Heart Transplant Report—2012. J. Heart and Lung Transplant. 2012; 31 (10): 1052-1064. 26. Toledo E. et al. Functional restitution of cardiac control in heart transplant patients. Amer. J. Physiol - Regulatory, Integrative and Comparative Physiology. 2001; 282 (3): R900-R908.
27. Überfuhr P. Signs of vagal reinnervation 4 years after heart transplantation in spectra of heart rate variability. Eur. J. Cardio-Thoracic Surgery. 1997; 12 (6): 907-912.
28. Wilson R. et al. Evidence for structural sympathetic reinnervation after orthotopic cardiac transplantation in humans. Circulation. 1991; 83 (4): 1210-1220.