Современные неинвазивные методы исследования в диагностике некомпактного миокарда левого желудочка
ИННОВАЦИИ
Дата публикации: декабря 20, 2014
Ключевые слова
кардиомиопатия
некомпактный миокард
левый желудочек
эхокардиография
магнитно-резонансная томография
некомпактный миокард
левый желудочек
эхокардиография
магнитно-резонансная томография
Как цитировать
Алехин М., Сидоренко Б., Ерохина М., Стукалова О. Современные неинвазивные методы исследования в диагностике некомпактного миокарда левого желудочка // Кремлевская медицина. Клинический вестник. 2014. Т. № 3. С. 19-23.
Аннотация
Некомпактный миокард левого желудочка (НМЛЖ) относится к редкой форме кардиомиопатий. В работеобследовано 15 больных НМЛЖ. С помощью метода эхокардиографии выделены три формы НМЛЖ и описаныклинико-функциональные изменения миокарда при каждой из них. Определено, что у больных НМЛЖ имеетсянарушение систолической и диастолической функции левого желудочка и наблюдается обратная зависимость междуколичеством сегментов с некомпактным миокардом и фракцией выброса левого желудочка. На основании сопоставлениярезультатов эхокардиографии и магнитно-резонансной томографии показана высокая диагностическая ценность обоихнеинвазивных методов в диагностике НМЛЖ.Ключевые слова: кардиомиопатия, некомпактный миокард, левый желудочек, эхокардиография, магнитно-резонансная томография.Noncompact myocardium of the left ventricle (NCMLV) is a rare form of cardiomyopathy. In our study 15 patients withNCMLV have been examined. Using echocardiographic examination we have defined three NCMLV forms and describedclinico-functional changes in each of them. It has been found out that patients with NCMLV have disorders in their systolic anddiastolic functions in the left ventricle. We have also seen the inverse relationship between the number of segments with noncompactmyocardium and the left ventricle ejection fraction. Comparative analysis of the results obtained at echocardiography andat MRI examination has shown that both noninvasive diagnostic techniques have high diagnostic value for revealing NCMLV.Кey words: cardiomyopathy, noncompact myocardium, left ventricle, echocardiography, magnet-resonance tomography.Литература
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5 – P. 372–375.
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report // J. Cardiol. – 2004. – Vol. 44. – № 1. – P. 21–25.
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Kaufmann. Echocardiographic and pathoanatomical characteristics
of isolated left ventricular non-compaction: a step towards
classification as a distinct cardiomyopathy // Heart. – 2001. – Vol.
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12. Oechslin E.N., Attenhofer Jost C.H., Rojas J.R. et al.
Long-term follow-up of 34 adults with isolated left ventricular
noncompaction: a distinct cardiomyopathy with poor prognosis // J.
Am. Coll. Cardiol. – 2000. – Vol. 36. – P. 493–500.
13. Sengupta P.P., Mohan J.C., Mehta V., Jain V., Arora R.,
Pandian N.G., Khandheria B.K. Comparison of echocardiografic
features of noncompaction of the left ventricule in adults versus
idiopatic dilated cardiomyopathy in adults // Am. J. Cardiol. –
2004. – Vol. 94. – P. 389–391.
14. Espinola-Zavaleta N., Soto M.E., Castellanos L.M.,
Jativa-Chaves S., Keirns C. Non-compacted cardiomyopathy:
clinical-echocardiographic study // Circulation. – 2006. – Vol. 4.
– P. 35–45.
15. Stollberger C., Finsterer J., Blazek G. Left ventricular
hypertrabeculation/ noncompaction and association with additional
cardiac abnormalities and neuromuscular disorders // Am. J.
Cardiol. – 2002. – Vol. 90. – P. 899–902.
16. Hany T.F., Jenni R., Debatin J.F. MR appearance of
isolated noncompaction of the left ventricle // J. Magn. Reson.
Imaging. – 1997. – Vol. 7. – P. 437–438.
17. Petersen S.E., Selvanayagam J.B., Wiemann F., Robson
M.D., Watkins H., Neubauer S. Left ventricular noncompaction.
Insights from cardiovascular magnetic resonance imaging // J. Am.
Coll. Cardiol. – 2005. – Vol. 46. – P. 101–105.
1999. – С. 7–13, 86–89.
2. Elliot P., Andersson B., Arbustini E., Biliska Z. et al.
Classification of the cardiomyopathies: a position statement from
the European society of cardiology working group on myocardial
and pericardial diseases // Eur. Hart. J. – 2008. – V.29 – P.270–
276.
3. Kenton A.B., Sanchez X., Coveler R.J., Makar K.A.,
Jimenez S., Ichida F., Murphy R.T., Elliott P.M., McKenna W.,
Bowles N.E., Towbin J.A., Bowles K.R. Isoleted left ventricular
noncompaction is rarely caused by mutations in G4.5, α-dystrobrevin
and FK Binding Protein 12 // Mol. Genet. Metab. – 2004. – Vol.
82. – P. 162–166.
4. Freedom R.M., Yoo S.J., Rerrin D., taylor G., Petersen
S., Andersjn R.H. The morphological spectrum of ventricular
noncompaction // Cardiol. of Young. – 2005. – Vol. 15. – P. 345–
264.
5. Pignatelli R.H., McMahon C.J., Dreyer W.J. et al. Clinical
characterization of left ventricular noncompaction in children: a
relatively common form of cardiomyopathy // Circulation. – 2003.
– Vol. 108. – P. 2672–2678.
6. Stollberger C., Finsterer J. Left ventricular
hypertrabeculation/ noncompaction // J. Am. Soc. Echocardiogr.
– 2004. – Vol. 17. – P. 91–100.
7. Sleurs E., Luc De Catte, Abraham Benatar. Prenatal
diagnosis of isolated ventricular noncompaction of the myocardium
// Pediatr. Cardiol. – 1996. – Vol. 17. – P. 42–45.
8. Chin T.K., Perloff J.K., Williams R.G. et al. Isolated
noncompaction of left ventricular myocardium: a study of eight cases
// Circulation. – 1990. – Vol. 82. – P. 507–513.
9. Corrado G., Santarone M., Miglierina E., Beretta S.,
Frattini T., Tadeo G., Manzzilo G.F., Tagliagamber L.M. Isolated
noncompaction of the ventricular myocardium. A study in an adult
male and literature review // Iltal. Heat. J. – 2000. – Vol. 1. – №
5 – P. 372–375.
10. Takashima A., Shimizu M., Tatsumi K., Shima T., Miwa
Y. Isolated left ventricular noncompaction in the elderly: a case
report // J. Cardiol. – 2004. – Vol. 44. – № 1. – P. 21–25.
11. Jenni R., E Oechslin, J Schneider, C Attenhofer Jost, P A
Kaufmann. Echocardiographic and pathoanatomical characteristics
of isolated left ventricular non-compaction: a step towards
classification as a distinct cardiomyopathy // Heart. – 2001. – Vol.
86. – № 6. – P. 666–671.
12. Oechslin E.N., Attenhofer Jost C.H., Rojas J.R. et al.
Long-term follow-up of 34 adults with isolated left ventricular
noncompaction: a distinct cardiomyopathy with poor prognosis // J.
Am. Coll. Cardiol. – 2000. – Vol. 36. – P. 493–500.
13. Sengupta P.P., Mohan J.C., Mehta V., Jain V., Arora R.,
Pandian N.G., Khandheria B.K. Comparison of echocardiografic
features of noncompaction of the left ventricule in adults versus
idiopatic dilated cardiomyopathy in adults // Am. J. Cardiol. –
2004. – Vol. 94. – P. 389–391.
14. Espinola-Zavaleta N., Soto M.E., Castellanos L.M.,
Jativa-Chaves S., Keirns C. Non-compacted cardiomyopathy:
clinical-echocardiographic study // Circulation. – 2006. – Vol. 4.
– P. 35–45.
15. Stollberger C., Finsterer J., Blazek G. Left ventricular
hypertrabeculation/ noncompaction and association with additional
cardiac abnormalities and neuromuscular disorders // Am. J.
Cardiol. – 2002. – Vol. 90. – P. 899–902.
16. Hany T.F., Jenni R., Debatin J.F. MR appearance of
isolated noncompaction of the left ventricle // J. Magn. Reson.
Imaging. – 1997. – Vol. 7. – P. 437–438.
17. Petersen S.E., Selvanayagam J.B., Wiemann F., Robson
M.D., Watkins H., Neubauer S. Left ventricular noncompaction.
Insights from cardiovascular magnetic resonance imaging // J. Am.
Coll. Cardiol. – 2005. – Vol. 46. – P. 101–105.