Transient global amnesia in the practice of a neurologist

Abstract

The literature does not fully cover the issues of etiology and clinical picture of transient global amnesia. For the first time, one of the forms of transient memory disorders in adults is described in 1956. M.B. Bender. This problem was dealt with by specialists such as G. Crowel, M. Alexander, M. Freedman and co-workers. (1984). More than 3,000 cases were analyzed and a conclusion was made on prevalence among the population. In the Soviet literature the description of this syndrome has been encountered since the 80s of the XX century. TGA in the world studied by many specialists, despite on that find a single mechanism for starting this pathology. Therefore, this work is actual today. The article presents data on transient global amnesia, the main clinical criteria, the difficulties of differential diagnosis. From 2013 to 2017, under our supervision with this pathology, there were 46 patients. All patients are divided into 2 age groups: the 1st from 50 to 60 years, the 2nd from 60 and older. In the first group, 9 patients were observed, 4 (8.6%) men and 5 (10.9%) women. In the second group, 37 patients were observed, 10 of them (21.8%) men and 27 (58.7%) women. Objective: To clarify concomitant diseases, provoking factors in patients undergoing transient global amnesia, and also analyzed data from additional research methods (Ultrasound duplex scanning of brachiocephalic vessels, Magnetic resonance imaging of the brain). Materials and methods: The basis of the study is the principle of complex clinical and statistical analysis for the study of transient global amnesia syndrome in patients with chronic cerebrovascular diseases. The study was conducted in neurological departments of the Federal Clinical Hospital “Central Clinical Hospital with a Polyclinic” of the Presidential Administration of the Russian Federation, the Clinical Hospital No. 1 (Volynskaya) of the Presidential Administration of the Russian Federation. Results: We have discovered an interesting pattern. The predominance of women is practically absent in the group of younger patients (from 50 to 60 years). Of the 9 patients in the first group, there are 5 (10.9%) women and 4 (8.6%) men. At the same time, in the older age group (60 years and over) of 37 patients, there were 27 (58.7%) women and only 10 (21.8%) men. In this group, there is a significant almost 3-fold greater prevalence of women over men.